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1. Marketing authorisation status in the assessment of ATC and DDD requests
   To support a scientifically robust and consistent assessment of requests within the ATC/DDD methodology, the criteria applied in relation to the marketing authorisation (MA) status of the medicinal products on which an ATC/DDD request is based have been updated. Requests for ATC code assignment...
   
   
2. Use of ATC/DDD
   Implementation and maintenance of the ATC/DDD methodologyWhen the decision to introduce and use the ATC/DDD methodology is taken, it is essential to realize that its proper use inevitably includes an important and time-consuming first step: Each pharmaceutical product has to be linked to the...
   
   
3. ATC classification of combinations of opioids and other analgesics
   The ATC classification of opioids in combination with other analgesics was on the agenda for the International Working Group for Drug Statistics Methodology meeting in October 2015. A proposal to classify all combination of opioids and other analgesics in a new ATC 4th level N02AJ Opioids in...
   
   
4. Clarification on complementary, homeopathic and herbal veterinary products in ATCvet
   The ATCvet Working Group has clarified the classification of complementary, homeopathic, and herbal traditional medicinal products for veterinary use. Generally, these products are not included in the ATCvet system. However, exceptions can be made for products that regulatory authorities have...
   
   
5. ATC/DDD request submission
   All ATC/DDD-related requests should be submitted electronically here. This applies to requests for: New ATC codes New DDDs Alterations Objections to temporary decisions of the WHO Advisory Group for Drug Statistics Methodology that are open for comments/objections (see current list and...
   
   
6. ATCvet Meeting 2023
   Documents to the ATCvet meeting in Oslo November 2023
   agenda 2023.pdfpoint_3_introducution to ATCvet.pdfpoint_5_New ATCvet codes 2023.pdfpoint_6_classification of the mesenchymal stem stromal cell products Canimezon™ and Canipren™.pdfpoint_7_alteration of the ATCvet code for dinitolmide.pdfpoint_8 alteration of the ATCvet code QI10AB03...
   
   
7. Application for DDD
   Data requirementsThe following information is required when requesting a new DDD: Dose ranges and dosing instructions for each indication in the product information approved by one or more major regulatory authorities Proposal for a DDD justified by the submitted information. Status concerning...
   
   
8. Definition and general considerations
   Definition and introductionThe basic definition of the defined daily dose (DDD) is: The DDD is the assumed average maintenance dose per day for a drug used for its main indication in adults. The DDD is a unit of measurement and does not necessarily reflect the recommended or Prescribed Daily Dose...
   
   
9. Application for ATC alterations
   Principles for ATC alterationsAs the selection of drugs and their uses are continually changing and expanding, regular revisions of the ATC system will always be necessary. Changes in the ATC classification should be kept to a minimum. An important aim is to keep a stable classification system...
   
   
10. Structure and principles
    Structure In the ATC classification system, the active substances are classified in a hierarchy with five different levels. The system has fourteen main anatomical/pharmacological groups or 1st levels. Each ATC main group is divided into 2nd levels which could be either pharmacological or...
    
    
11. The EphMRA classification system
    The ATC classification system was originally based on the same main principles as the Anatomical Classification developed by the European Pharmaceutical Market Research Association (EphMRA) and the Pharmaceutical Business Intelligence and Research Group (PBIRG). In the EphMRA classification,...
    
    
12. History
    The field of Drug Utilization Research (DUR) began attracting attention in the 1960’s. A WHO symposium in 1969 highlighted the need for an internationally accepted classification system for drug utilization studies. As a result the Drug Utilization Research Group (DURG) was established and...
    
    
13. Application for ATC codes
    Data requirementsThe following data should be submitted when requesting an ATC code for a substance: Chemical structure and relationship to similar drugs Pharmacology and mechanism of action and relationships to similar drugs Main indication as shown in the product information in major...
    
    
14. About the course
    Course: Introduction to the ATC/DDD methodology The “Introduction to the ATC/DDD methodology” course gives a general overview of the ATC/DDD methodology. In this course, you will be introduced to the basic principles of the Anatomical Therapeutic Chemical (ATC) classification system...
    
    
15. Practical information
    VenueNorwegian Institute of Public Health, Myrens verksted 6H, 0473 Oslo, Norway. Details on how to reach us will be sent to all participants. DatesThis is a 2-full-day (from 9.00 to 16.30) course and will be held on 26 and 27 November 2026. LanguageEnglish. Participation fee€ 450,-. ...
    
    
16. ATCvet
    The ATCvet system for the classification of veterinary medicines is based on the same overall principles as the ATC system for substances used in human medicine. In most cases an ATC code exists which can be used to classify a product in the ATCvet system. The ATCvet code is then created by placing...
    
    
17. WHO Collaborating Centre for Drug Statistics Methodology
    The Centre was established in 1982. The Centre is located in Oslo at the Norwegian Institute of Public Health and funded by the Norwegian government. The Centre's main activities are development and maintenance of the ATC/DDD system, including: To classify drugs according to the ATC system. To...
    
    
18. Relationship - ATCvet and the ATC (human)
    The ATCvet system is based on and annually updated according to the changes in the ATC system for substances used in human medicine. Many of the substances may thus not have a well established use or may be of limited relevance for veterinary medicine. However, pharmacotherapy in veterinary...
    
    
19. Application for ATCvet codes
    Requests for classifications of new substances should be addressed to the WHO Collaborating Centre for Drug Statistics Methodology. It is recommended that requests be made using the special application form obtainable from the Centre (see Application form). A new medicinal substance is normally...
    
    
20. Classification of combined preparations
    Preparations containing two or more active components are classified as combined products in accordance with the principles of the ATC system. The main therapeutic use decides which ATCvet code is to be used. Combined products are classified according to two main principles: Combined...
    
    
21. Classification of plain preparations
    Plain/monovalent preparations are defined as: Preparations containing one active component (including stereoisomeric mixtures), and additional substances intended to increase the stability of the preparations (e.g. acetylsalicylic acid + ascorbic acid), or increase the duration of the effect...
    
    
22. General principles
    The ATCvet system for the classification of veterinary medicines is based on the same overall principles as the ATC system for substances used in human medicine. In most cases, an ATC code exists which can be used to classify a product in the ATCvet system. The ATCvet code is then created by...