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C CARDIOVASCULAR SYSTEM

This group comprises substances used for the treatment of cardiovascular conditions.
Drugs used for the treatment of hypertension are classified in C02 - Antihypertensives, C03 - Diuretics, C07 - Beta blocking agents, C08 - Calcium channel blockers, and C09 - Agents acting on the renin-angiotensin system. For the classification of combination products of antihypertensives from different ATC groups, the following ranking should be used, from higher to lower precedence: C09, C07, C08, and C03.


C03 DIURETICS

This group comprises diuretics, plain and in combination with potassium or other agents. Vasopressin antagonists are also included in this group. Potassium-sparing agents are classified in C03D and C03E.
Combinations with digitalis glycosides, see C01AA.
Combinations with antihypertensives, see C02L - Antihypertensives and diuretics in combination.
Combinations with beta blocking agents, see C07B - C07D.
Combinations with calcium channel blockers, see C08.
Combinations with agents acting on the renin angiotensin system, see C09B and C09D.

The DDDs for diuretics are based on monotherapy. Most diuretics are used both for the treatment of edema and hypertension in similar doses and the DDDs are therefore based on both indications.
The DDDs for combinations correspond to the DDD for the diuretic component, except for ATC group C03E, see comments under this level.


C03C HIGH-CEILING DIURETICS

This group comprises high-ceiling diuretics (loop-diuretics) e.g. furosemide.
Combinations with potassium-sparing agents, see C03EB.


C03CA Sulfonamides, plain
C03CB Sulfonamides and potassium in combination

The 5th levels correspond to those in C03CA. See example in C03AB.

C03CC Aryloxyacetic acid derivatives
C03CD Pyrazolone derivatives
C03CX Other high-ceiling diuretics

All high-ceiling diuretics which cannot be classified in the preceding groups are classified here.

Last updated: 2024-01-26