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This group comprises substances used for the treatment of cardiovascular conditions.
Drugs used for the treatment of hypertension are classified in C02 - Antihypertensives, C03 - Diuretics, C07 - Beta blocking agents, C08 - Calcium channel blockers, and C09 - Agents acting on the renin-angiotensin system. For the classification of combination products of antihypertensives from different ATC groups, the following ranking should be used, from higher to lower precedence: C09, C07, C08, and C03.

See also C03 - Diuretics, C07 - Beta blocking agents, C08 - Calcium channel blockers and C09 - Agents acting on the renin-angiotensin system.
Antihypertensives are mainly classified at 3rd levels according to the mechanism of action. Most headings are self-explanatory:
C02A Antiadrenergic agents, centrally acting
C02B Antiadrenergic agents, ganglion-blocking
C02C Antiadrenergic agents, peripherally acting
C02D Arteriolar smooth muscle, agents acting on
C02K Other antihypertensives
C02L Antihypertensives and diuretics in combination
C02N Combinations of antihypertensives in ATC gr. C02

This group comprises all antihypertensives which cannot be classified in groups C02A-D, C02L, C02N, C03 - Diuretics, C07 - Beta blocking agents, C08 - Calcium channel blockers or C09 - Agents acting on the renin-angiotensin system.

All agents classified in this group are for treatment of pulmonary arterial hypertension (PAH).
Other agents used for treatment of PAH such as phosphodiesterase inhibitors (e.g. sildenafil) or prostaglandins (e.g. epoprostenol) are classified in G04BE and in B01AC respectively.

ATC code	Name	DDD	U	Adm.R	Note
C02KX01	bosentan	0.25	g	O
C02KX02	ambrisentan	7.5	mg	O
C02KX03	sitaxentan	0.1	g	O
C02KX04	macitentan	10	mg	O
C02KX05	riociguat	4.5	mg	O
C02KX52	ambrisentan and tadalafil
C02KX54	macitentan and tadalafil

List of abbreviations