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Inhaled antiinfectives are classified in ATC group J - Antiinfectives for systemic use.


Varenicline nasal spray used for dry eye disease is classified in S01XA.


This group comprises preparations for local treatment in nasal congestion (e.g. sympathomimetics) or for prophylaxis and treatment of allergic rhinitis (e.g. corticosteroids, cromoglicate preparations). Most of the products are nasal drops, nasal sprays or nasal inhalants. Formulations approved for eye, ear and nose are classified in S03.
See also R01B - Nasal decongestants for systemic use, and
R06 - Antihistamines for systemic use.

The DDDs are based on treatment of both nostrils.

R01AA Sympathomimetics, plain

Small amounts of antiseptics etc. are allowed at each 5th level.
Combinations with antibiotics, antihistamines, ipatropium bromide etc. are classified in R01AB, while combinations with corticosteroids are classified in R01AD.

The DDDs are based on the treatment of acute rhinitis.

R01AB Sympathomimetics, combinations excl. corticosteroids

Combinations with e.g. antibiotics, antihistamines and ipatropium bromide are classified in this group.
This group also includes preparations with two or more sympathomimetics. These combinations are classified in a ranking according to the ATC codes, e.g. substances classified in R01AB01 take precedence over substances classified in R01AB02 etc.
Combinations of phenylephrine and lerimazoline are classified in R01AB01.
Combinations of tetracaine and oxymetazoline for nasal application used as local dental anesthetics are classified in N01BA.

The DDDs are based on the treatment of rhinitis. DDDs are given in volume (i.e. ml). Most of the products classified in this group are combinations with antihistamines. So far, all these products are given a fixed DDD of 0.8 ml.

R01AC Antiallergic agents, excl. corticosteroids

Antihistamines, cromoglicate disodium and analogues are classified here. Combinations with corticosteroids are classified in R01AD.

The DDD of cromoglicic acid is based on the prophylaxis of rhinitis. The DDDs of the antihistamines are based on the maintenance treatment of rhinitis.

R01AD Corticosteroids

Combinations of corticosteroids with antiinfectives, sympathomimetics, antihistamines etc. are classified in this group at separate 5th levels by using the 50-series.
Fluticasone propionate is classified in R01AD08.

The DDDs are mainly based on the starting dose in the treatment of rhinitis.

R01AX Other nasal preparations

This group comprises antiinfectives, antiseptics, mucolytics etc. which cannot be classified in the preceding groups.
ATC level R01AX10 is an old level where rather obsolete nasal preparations and sodium chloride nasal products are classified. The level R01AX30 is for nasal combination products which cannot be classified in the preceding groups.
Combinations of ipatropium bromide and xylometazoline are classified in R01AB.

The DDDs are based on the treatment of rhinitis.

Last updated: 2024-01-26