Postal address:
Norwegian Institute of Public Health
WHO Collaborating Centre for Drug Statistics Methodology
Postboks 222 Sk°yen
0213 Oslo

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Myrens verksted 6H
0473 Oslo

Tel:  +47 21 07 81 60

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This group comprises preparations used in the treatment of neoplastic diseases, and immunomodulating agents.
Corticosteroids for systemic use, see H02.


Combination products are classified in L01XY - Combinations of antineoplastic agents, except for combinations of monoclonal antibodies or antibody drug conjugates which are classified in L01FY.
Detoxifying agents used in connection with high dose treatment of antineoplastic agents are classified in V03AF (e.g. calcium folinate).
Radiopharmaceuticals used in the treatment of cancer are classified in V10X.

DDDs have been established for the protein kinase inhibitors in L01E only.
No DDDs have been established for substances classified in ATC 3rd level L01A, L01B, L01C, L01D, L01F or L01X. This is because of highly individualised use and wide dosage ranges. The doses used vary substantially because of various types and severity of neoplastic diseases, and also because of the extensive use of combination therapy.
The consumption of antineoplastic agents is in some countries measured in grams. This is recommended as a method to be used internationally for these particular agents.


This group comprises antineoplastic preparations which cannot be classified in the preceding groups.

L01XA Platinum compounds
L01XB Methylhydrazines
L01XD Sensitizers used in photodynamic/radiation therapy
L01XF Retinoids for cancer treatment
L01XG Proteasome inhibitors
L01XH Histone deacetylase (HDAC) inhibitors
L01XJ Hedgehog pathway inhibitors
L01XK Poly (ADP-ribose) polymerase (PARP) inhibitors
L01XL Antineoplastic cell and gene therapy

This group includes both genetically modified and unmodified cell therapies.

L01XX Other antineoplastic agents

Also antineoplastic agents for dermatological use are classified here.
All asparaginases regardless of origins are classified in L01XX02. The
50-series codes are used for single substances due to lack of numbers.
Phosphatidylinositol-3-kinase (Pi3K) inhibitors are classified in L01EM.

L01XY Combinations of antineoplastic agents

Combinations of antineoplastic agents in L01 - Antineoplastic agents are classified in this group, except for combinations of monoclonal antibodies or antibody drug conjugates which are classified in L01FY.

Last updated: 2024-01-26