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This group comprises substances used for the treatment of cardiovascular conditions.
Drugs used for the treatment of hypertension are classified in C02 - Antihypertensives, C03 - Diuretics, C07 - Beta blocking agents, C08 - Calcium channel blockers, and C09 - Agents acting on the renin-angiotensin system. For the classification of combination products of antihypertensives from different ATC groups, the following ranking should be used, from higher to lower precedence: C09, C07, C08, and C03.


See also C03 - Diuretics, C07 - Beta blocking agents, C08 - Calcium channel blockers and C09 - Agents acting on the renin-angiotensin system.
Antihypertensives are mainly classified at 3rd levels according to the mechanism of action. Most headings are self-explanatory:
C02A Antiadrenergic agents, centrally acting
C02B Antiadrenergic agents, ganglion-blocking
C02C Antiadrenergic agents, peripherally acting
C02D Arteriolar smooth muscle, agents acting on
C02K Other antihypertensives
C02L Antihypertensives and diuretics in combination
C02N Combinations of antihypertensives in ATC gr. C02

The oral DDDs are based on the average doses needed to reduce the blood pressure to a normal level in patients with mild-moderate hypertension.
Parenteral DDDs are based on dosages used for the treatment of hypertensive crises and are based on the content of the active ingredient pr. vial (ampoule).


See also C08 - Calcium channel blockers.

C02DA Thiazide derivatives

Parenteral preparations of diazoxide are classified here.
Oral preparations containing diazoxide for treatment of hypoglycemia are classified in V03AH.

C02DB Hydrazinophthalazine derivatives

Combinations with diuretics, see C02LG - Hydrazinophthalazine derivatives and diuretics.
Combinations of isosorbide dinitrate and hydralazine are classified in C01DA - Organic nitrates.

The oral DDD of dihydralazine is higher than the parenteral DDD. The parenteral DDD is given as the chloride salt while the oral DDD is given as the mesylate salt.

C02DC Pyrimidine derivatives

Minoxidil for systemic use is classified here.
Dermatological preparations containing minoxidil are classified in D11AX.

C02DD Nitroferricyanide derivatives
C02DG Guanidine derivatives

Last updated: 2024-01-26